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Propolis + MGO 823: The Science Behind Our Hand Cream

3 Mar 2026

Propolis + MGO 823: The Science Behind Our Hand Cream

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Propolis + MGO 823: The Science Behind Our Hand Cream

Author:  Sara Samavati & Dr. Isaac Flitta Why Hands Are The Hardest Skincare Challenge Your hands face more abuse than any other part of your body. They're washed 20-50 times daily, exposed to harsh soaps, subjected to temperature extremes, immersed in water, covered in sanitizer, and constantly touching surfaces that strip away protective oils. Then we expect them to look moisturized, feel soft, and heal quickly from cracks, splits, and inflammation. It's an impossible task—unless you...

  • 3 hours ago
  • 7 min read

Author: Sara Samavati & Dr. Isaac Flitta


Why Hands Are The Hardest Skincare Challenge

Your hands face more abuse than any other part of your body.

They're washed 20-50 times daily, exposed to harsh soaps, subjected to temperature extremes, immersed in water, covered in sanitizer, and constantly touching surfaces that strip away protective oils.


Then we expect them to look moisturized, feel soft, and heal quickly from cracks, splits, and inflammation.


It's an impossible task—unless you understand both skin barrier science AND quality control for natural bioactive ingredients.


That's why we created our Nourishing Hand Cream with MGO 823+ mānuka honey and high-grade bee propolis. Not because we wanted another product in our line, but because neither of us could find a hand cream that actually solved chronic hand dermatitis using natural ingredients with verified potency.

Let me (Sara) explain the formulation science, then Dr. Flitta will explain why the quality control matters.


How A Simple Lip Balm Led To Hand Cream (Sara Samavati)

When I first started experimenting with mānuka honey skincare, I made a simple lip balm with bee propolis. My background in Animal Husbandry and Agriculture from Germany taught me to understand how bees create these substances. My Organic Skincare Formulation training from the UK taught me how to formulate with them.

The lip balm was simple but effective. People with chronically chapped lips healed. The positive reviews were overwhelming.

But the feedback that caught my attention: "This is the only thing that's helped my hand eczema. Can you make hand cream?"

That's when I realized: the same bioactive properties that healed lips could heal the most challenging skin condition—chronic hand dermatitis.


The Skin Barrier Problem

Healthy skin has a barrier made of three components:

  1. Lipid matrix (ceramides, cholesterol, fatty acids)

  2. Natural moisturizing factor (amino acids, urea, lactic acid)

  3. Intact corneocytes (flattened skin cells)


Hand washing disrupts all three. Soap emulsifies lipids, water dilutes natural moisturizing factor, and mechanical friction damages corneocytes.

Most hand creams try to replace what's lost by adding:

  • Emollients (make skin feel smooth)

  • Humectants (attract water)

  • Occlusives (seal moisture in)

This works temporarily. But it doesn't address why your hands keep cracking despite using cream 5 times a day.


The problem isn't just dryness—it's inflammation and disrupted barrier repair.

Here's what happens with chronic hand eczema or dermatitis:

  1. Barrier damage triggers inflammatory response

  2. Inflammation further damages barrier

  3. Damaged barrier lets irritants penetrate deeper

  4. Deeper penetration causes more inflammation

  5. The cycle repeats

You can moisturize all day, but if you don't break the inflammation loop, your hands never fully heal.


Why We Chose MGO 823+ (The Formulation Decision)

When I proposed using mānuka honey in hand cream, Isaac asked me a question I hadn't fully considered:


"What's the optimal MGO concentration for skin barrier repair without irritation?"

Most brands just use "mānuka honey" without specifying MGO level, or they go for maximum potency (MGO 1000+) assuming more is better.

But my training taught me that optimal ≠ maximum.

From my research and formulation experiments:


  • MGO 100-400: Moisturizing and mildly antibacterial

  • MGO 400-800: Significantly antibacterial and anti-inflammatory

  • MGO 800-1000+: Maximum antibacterial but potential for irritation in damaged skin


For hands that are washed constantly and already irritated, I needed:

  • Strong anti-inflammatory action (to break the cycle)

  • Antibacterial properties (to prevent secondary infection in cracks)

  • But not so potent it irritates compromised barrier

MGO 823 hit the sweet spot: clinical-level potency without the harshness of ultra-high MGO concentrations on damaged skin.

The Propolis Addition (From Bee Biology To Skincare)

My Master's in Animal Husbandry taught me how bees create propolis—they collect plant resins and combine them with enzymes to create this incredible protective substance for their hives.

Propolis contains over 300 bioactive compounds including:


  • Flavonoids (anti-inflammatory, antioxidant)

  • Phenolic acids (antimicrobial)

  • Essential oils (barrier support)


But here's what my agricultural background taught me: propolis quality varies enormously based on what plants the bees have access to, time of year, and hive location.


Propolis from hives near specific plant species has higher flavonoid content. Propolis collected in spring differs from autumn propolis.

Most skincare formulators buy "cosmetic-grade propolis" and trust the supplier.

Isaac and I test for specific flavonoid content. Specifically quercetin, galangin, and pinocembrin—the three flavonoids with the strongest published evidence for skin barrier repair.


Our propolis tests at minimum 30-35% total flavonoid content with verified levels of all three target compounds.

The Quality Control That Makes It Work (Dr. Isaac Flitta, PhD)

Sara's formulation expertise created an elegant product. My engineering background ensures it performs consistently.

I've spent decades working with materials that have to perform under stress. Whether it's an aluminium component at 35,000 feet or a fracture plate inside a human body, you can't just assume your material will perform—you test, verify, and document.

Mānuka honey and bee propolis are natural materials. That means batch-to-batch variation is inevitable unless you control for it.

Here's what we verify for every production batch:


For Mānuka Honey:

  • MGO concentration (independent lab testing)

  • Moisture content (affects stability)

  • HMF levels (marker of heat damage)

  • Purity (no additives, no dilution)

For Bee Propolis:

  • Flavonoid profile (HPLC analysis)

  • Heavy metal content (< 10 ppm)

  • Microbial load (< 100 CFU/g)

  • Oxidative stability


This isn't standard in cosmetics. Most brands test the FORMULA for stability and safety, but they don't test every BATCH of raw ingredients.

We do both.

Why? Because Sara's formulation is engineered for MGO 823 honey with 30-35% flavonoid propolis. If the batch actually contains MGO 750 honey with 25% flavonoid propolis, the performance changes.

We can't control natural variation in raw ingredients. But we CAN refuse to use any batch that doesn't meet our specifications.

The Formula: What's Actually In It (Sara)

Our hand cream contains:


Active Ingredients (verified and tested):

  • MGO 823+ Mānuka Honey (antibacterial, anti-inflammatory, barrier support)

  • High-grade Bee Propolis 30-35% flavonoids (anti-inflammatory, antioxidant)

Supporting Ingredients (organic and natural):

  • Shea Butter (occlusive barrier protection)

  • Jojoba Oil (mimics skin sebum)

  • Vitamin E (antioxidant, prevents oxidation of propolis)

  • Beeswax (seals and protects)

  • Aloe Vera (soothing, healing)


What's NOT in it:

  • Parabens

  • Synthetic fragrances

  • Phthalates

  • Mineral oil

  • Harsh preservatives

The base is engineered to:

  1. Deliver MGO and flavonoids to skin (penetration)

  2. Protect honey from degradation (stability)

  3. Seal barrier without feeling greasy (texture)

  4. Maintain potency for 24 months (shelf life)

Most hand creams are oil-in-water emulsions that feel light but wash off immediately. Ours is a water-in-oil emulsion that absorbs but creates a protective layer that survives hand washing.



From Lip Balm Success To Nine-Product Line

After our lip balm became so popular from positive reviews, we expanded carefully. We now have nine products in our skincare line—all formulated by me with Isaac's engineering precision mind ensuring quality.

We didn't just create products to fill shelf space. Each product exists because:

  1. Mānuka honey or bee propolis offers unique advantages

  2. I could formulate it elegantly using organic principles

  3. Isaac could verify and control the active ingredient quality

  4. It solved a real problem better than alternatives

This hand cream represents our partnership perfectly:

  • My formulation expertise and understanding of bee products

  • Isaac's quality control and materials science precision

  • Together creating therapeutic skincare with verified potency


Who This Is Actually For (Honest Assessment)

This hand cream is overkill if you have:

  • Normal, healthy hands that get occasionally dry

  • Minor dryness from winter weather

  • Hands that respond fine to basic moisturizer

This hand cream is engineered for:

  • Chronic hand eczema or dermatitis

  • Occupational hand damage (healthcare workers, chefs, cleaners)

  • Hyperkeratotic hand conditions

  • Hands that crack, split, or bleed regularly

  • People who've tried everything else without lasting results


If your hands are just a little dry, buy a good basic hand cream for $15. You don't need clinical-grade mānuka honey.

But if you've spent years cycling through dermatologist prescriptions, steroid creams, and $40 "eczema repair" formulas that work for two days and then stop, this is engineered specifically for you.


The Results We See (And The Timeline)

Here's what typically happens:

Week 1: Inflammation reduction. Hands feel less angry and reactive. Cracks start to close.

Week 2-3: Barrier strengthening. Hands tolerate soap/water better without immediately cracking again.

Week 4+: Sustained improvement. The inflammation loop is broken. Hands maintain integrity even with frequent washing.

This isn't magic. It's targeted delivery of anti-inflammatory compounds (propolis flavonoids) + antibacterial protection (MGO) + barrier support (shea, jojoba, beeswax) in quantities that actually matter.


How To Use It (Application Protocol)

For maintenance (healthy but stressed hands):

  • Apply after each hand washing

  • Focus on knuckles and fingertips

  • Let absorb 2-3 minutes before handling items

For active dermatitis/eczema:

  • Apply liberally 3-4x daily minimum

  • After washing, pat hands damp (don't fully dry)

  • Apply cream to damp hands (enhances penetration)

  • Use extra at night, consider cotton gloves for overnight treatment

  • Be consistent for minimum 2-3 weeks

The biggest mistake people make is using it sporadically. Chronic hand conditions need consistent barrier support while healing occurs.


Why We Made This (Personal Story)

Honestly? Because my hands (Sara speaking) were constantly affected by formulation work, and I couldn't find anything with verified potency and quality.


I knew from my agriculture training what compounds SHOULD work. I knew from my formulation training how to deliver them elegantly.


But I didn't have Isaac's quality control systems to verify that what I formulated actually performed consistently batch after batch.


Our partnership, my formulation expertise plus his engineering precision, created something neither of us could build alone.


This hand cream is now one of nine products in our line. Each one formulated by me, quality-controlled by Isaac, created because we saw a genuine need that bioactive honey could address better than alternatives.


If it works for a skincare formulator whose hands are in products all day, it'll work for healthcare workers, cleaners, chefs, and anyone else whose hands take daily abuse.


Sara Samavati is Business Partner and Director of Skincare Solutions at Tōtika Health. She holds a Master's in Animal Husbandry and Agriculture from Germany and trained as an Organic Skincare Formulator in the UK.


Dr. Isaac Flitta is Founder & CEO of Tōtika Health, holding a PhD in Materials Science and MPhil in Biomedical Engineering. As Founding Member #FM00007 of the NZ Apiculture Industry Body, he applies aerospace-grade quality control to premium mānuka honey production.


 
 
 

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